Drug Price List - List of Generic Names in alphabetical order starting with alphabet M Font : A- A+Price List Updated on February, 2, 2. Medindia's drug database currently has 3. Generics. Price list is displayed on all the brands of the generics. The database is kept current and the new generics are added as and when they become available in the pharmacies. However if a generic or brand you are looking for is missing from the list, please inform us and we will have it added. Browse the Drugs alphabetically. Disclaimer . The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including local taxes. These are only approximate indicative prices of the drug. Step Guide to Reverse Leptin Resistance & Thyroid Resistance. Are you having trouble losing weight? Or, better yet.. You can't lose weight no matter how much you exercise. You are constantly gaining weight even though you haven't changed your exercise or diet routine. You feel like your metabolism is unusually slow or damaged. You've tried 4+ different calorie restricted diets in your life (weight watchers, HCG diet, etc.)You used to be able to lose weight by dieting but you can't anymore. You think you have thyroid problems but the Doctor keeps telling you everything is . And we want this to happen (when it works correctly). When we have a lot of food to eat (and fat stores are high), our body is supposed to tell our brain to increase the metabolism of our body to start burning up that extra fuel. So by now you may be asking yourself.. If that’s the case, why does it feel like my metabolism is so low despite having a lot of excess fat in my body? Shouldn't my metabolism be high so that I can burn up this extra fat? The truth is that you SHOULD be doing that and if you aren't, then you may have the condition known as Leptin Resistance. So let's find out how that happens.. Over time your brain completely blocks out any leptin in the system. This process is similar to what occurs in the condition known as insulin resistance and type II diabetes. So your brain slows down the metabolism of your entire body and increases your appetite to try and compensate. This ultimately leads to more weight gain and higher leptin levels making the cycle even worse. They watch other people eating food, not exercising or living an unhealthy life without gaining weight or changing their body type. Meanwhile, patients with Leptin Resistance will gain weight if they don't follow a STRICT diet. Many patients with leptin resistance eat a calorie restricted diet simply to maintain their weight (this has to due with the metabolic damage that accompanies leptin resistance which we will discuss later). They don't necessarily mean you have it, but if you are suffering from more than 2 of the symptoms above then there is a high chance you might be. The presence of these symptoms should trigger the next step, which is serum blood testing. How to Diagnose Leptin Resistance. How can I Convert IU to mg/mcg and How can I Convert mg/mcg to IU? The converter permits the user to convert between international unit and weight of biologycal. Why? Because the fact that leptin levels remain elevated in the face of obesity is a clear signal that the normal feedback loop is dysregulated. You can see an example of a patient with leptin resistance and her labs below: In this result her fasting leptin level is 4. As a result you may need to be asking for these tests and reading posts like this to evaluate your lab result. Please also note that the lab will try to give you an approximate range for leptin level based off of your BMI. 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The lab makes observations about lab tests and notes that, for instance, patients with a BMI over 4. But this does NOT mean that it is normal, it just means that there are many others out there with leptin resistance. Uric acid levels act as a proxy for determining how well your body is metabolizing fructose. And fructose combined with a high fat diet can make Leptin Resistance worse. If Uric acid levels are > 5 then you know you are consuming too much fructose for your body or your liver is having difficulty metabolizing the fructose. The last test I like to order is Reverse T3. As leptin increases and your metabolism slows, your Reverse T3 level will increase. This is a compensatory reaction. Thyroid hormone is responsible for a large portion of your metabolism at baseline. So as leptin levels rise and you develop leptin resistance, your hypothalamus lowers your basal metabolic rate. Reverse T3 acts as a brake for your metabolism, so as leptin levels rise your reverse T3 will also rise - thus damaging and further slowing your metabolism. Anything higher than that indicates to me that there is a problem with thyroid conversion and likely metabolism. If your levels are out of range then you are suffering from Leptin resistance and most likely Thyroid resistance (which we will talk about below). You will have to ask your doctor for these tests. Leptin Resistance causes Thyroid Resistance. Aside from the fact that Leptin Resistance makes it almost impossible to lose weight, it also causes further issues with your thyroid gland. As Leptin levels increase and your brain slows down your metabolism, your body will start to convert Free T4 into Reverse T3. Reverse T3 actually competes on your cells for binding with the free and Active T3 hormone. The higher your reverse T3 levels, the lower your metabolism and the more likely you are to suffer from Hypothyroidism. This increase in Reverse T3 is known as . Often times the best treatment for patients with this condition is T3 only medication. In addition you may require a total reduction in your T4 thyroid medication to reduce the conversion of T4 to reverse T3. This connection between leptin, obesity and thyroid hormone is very powerful. In many cases it's hard to determine which condition came first considering that they all can worsen each other. Because of this, it's best to start with a comprehensive lab panel that includes testing beyond the leptin levels mentioned above. But in general healthy levels (assuming you aren't already on medication) are less than 1. Free T3: Should be in the upper 1/2 of the reference range (assuming you aren't taking thyroid medication)Free T4: Less important than T3, but gives you an idea about T4 to T3 conversion. Reverse T3: Should be less than 1. Total T3: Should be in the upper 1/2 of the reference range. Anti thyroid antibodies: As low as possible. Sex hormone binding globulin: 2. This gives you an estimation of tissue levels of thyroid hormone in the liver. In fact your Doctor isn't likely to even order the tests that you need to diagnose the condition unless you ask for them. This can fool you into thinking that your thyroid function is . The pattern I typically see in Leptin Resistance and Thyroid resistance looks like this: Low levels of Free T4. Mid- high levels of Free T3. High levels of Reverse T3. Low- normal levels of TSHEven Doctors who order the right tests can be fooled by those numbers, but the reality is that patients with these kind of numbers need more thyroid hormone (preferably T3) not LESS. In my experience most patients will need to do a combination of therapies to get the best results possible. Doing just one thing at a time isn't likely to produce results. It took various insults to get you to where you are now (diet, stress, lifestyle, hormone imbalances, etc.) and it will require multiple therapies to reverse the process. Get on the right type and dose of thyroid hormone. Many patients stand to benefit from the addition of . The reason T3 is so effective is because part of the problem with leptin resistance is that it causes T4 to reverse T3 conversion. It's important to under this point: T4 is required for conversion to reverse T3. If you remove T4 from the body then you won't have the substrate to produce reverse T3 from. Make sense? And this is exactly what taking T3 dose. You can bypass this conversion step so you . This can sometimes, paradoxically, . Even though NDT does contain some T3, it's still mostly T4 thyroid hormone. So reducing your dose of NDT may be necessary to reduce reverse T3 levels and help reduce leptin levels. This is a critical component of reversing leptin resistance. Optimize your exercise routine and do the right kind of exercises. When it comes to exercising, not all exercises are created equal. In addition, many patients are actually over training and may be making it more difficult to lose weight. Over- training leads to higher than normal cortisol levels which may alter insulin levels and ultimately make weight loss more difficult. If you have known leptin resistance then you will find the most benefit in doing high intensity interval training. HIIT has been shown to help reduce leptin levels long term (note this effect may take months). With these variables in mind it's best to start off slow with 1 session of 1. Just make sure you aren't over exercising which can make weight loss more difficult. There are multiple considerations (we will go over the others below) but for this section we want to focus on reducing inflammation with your diet. The addition of these . True - this change in your diet by itself will be necessary for reducing your leptin level, but it will not be enough by itself to reverse the condition. I call this the one ingredient diet. Meaning you only eat foods with one ingredient (apples, bananas, almonds, etc.). This is a very simple and clear way to dramatically improve your health. You can also find more resources here: Bottom line: Changing your diet will be necessary to reduce leptin levels but often will not be enough by itself for significant weight loss. Focus on natural whole food, anti inflammatory diets. Optimize your sleep (very important). Lack of sleep is associated with an increase in insulin/blood sugar levels, inflammation and may increase leptin levels and leptin resistance. While improving your sleep may not help you lose weight by itself, what it does is still very powerful. Getting at least 8 hours of sleep will help increase the velocity of your weight loss over time. Opposite to that, lack of sleep can also reduce how much weight you lose. For instance: Let's say you would have lost 1. Fortunately, improving your sleep isn't very difficult and you can start with some basic recommendations and ramp up the intensity as necessary. This is especially helpful if you are also suffering from depression or other mood disorders. Use 5. 0- 1. 00mg per night (1 hour prior to bed time). Melatonin: Melatonin can help promote a regular circadian rhythm. Start with dosing between 1- 3mg and take it approximately 3.
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